Russian veterinary journal Russian veterinary journal Российский ветеринарный журнал 2500-4379 88354 10.32416/2500-4379-2024-3-27-33 СОВРЕМЕННЫЕ ФАРМАКО- И БИОПРЕПАРАТЫ MODERN PHARMACOLOGICAL DRUGS & BIOPREPARATIONS СОВРЕМЕННЫЕ ФАРМАКО- И БИОПРЕПАРАТЫ Evaluation of the effectiveness of a new drug Kurs Uspokoin tablets for the correction of age-related cognitive impairment in cats Оценка эффективности нового лекарственного препарата Курс Успокоин таблетки для коррекции возрастных когнитивных нарушений у кошек Елизарова Елена Анатольевна Elizarova Elena Anatol'evna anatomifarmitox@mail.ru

кандидат биологических наук;

candidate of sciences in biology;

 Белоглазов Денис Валерьевич Beloglazov Denis Valer'evich

кандидат биологических наук;

candidate of sciences in biology;

 Мукасеев Сергей Владимирович Mukaseev Sergey Vladimirovich

кандидат ветеринарных наук;

candidate of veterinary sciences;

 Зейналов Орхан Ахмедович Zeynalov Orhan Ahmedovich

кандидат биологических наук;

candidate of sciences in biology;

 Федеральное государственное бюджетное учреждение высшего образования «Нижегородская сельскохозяйственная академия» Нижний Новгород Россия Nizhny Novgorod State Agricultural Academy Nizhnij Novgorod Russian Federation «Центр ветеринарной помощи» Дзержинск Россия «Center of the veterinary aid» Dzerzhinsk Russian Federation ФГБОУ ВО «Нижегородский государственный агротехнологический университет имени Л.Я. Флорентьева» (НГАТУ) Нижний Новгород Россия FSBEIo HE «Nizhny Novgorod State Agrotechnological University named after L.Ya. Florentiev» (NNSAU) Nizhny Novgorod Russian Federation ООО «НПК «СКиФФ» Москва Россия LLC «NPC «SKiFF» Moscow Russian Federation ООО «АГ «Аспект» Москва Россия LLC AG Aspect Moscow Russian Federation ООО «НВП «Астрафарм» Москва Россия LLC «RDE «Astrapharm» Moscow Russian Federation ООО «НПК «СКиФФ» Москва Россия LLC «NPC «SKiFF» Moscow Russian Federation ООО «АГ «Аспект» Москва Россия LLC «AG «Aspect» Moscow Russian Federation ООО «НВП «Астрафарм» Москва Россия LLC «RDE «Astrapharm» Moscow Russian Federation ООО «БиоФерон» Москва Россия LLC «BioFeron» Moscow Russian Federation ООО «НПК «СКиФФ» Москва Россия LLC «NPC «SKiFF» Moscow Russian Federation ООО «НВП «Астрафарм» Москва Россия LLC «RDE «Astrapharm» Moscow Russian Federation ООО «БиоФерон» Москва Россия LLC «BioFeron» Moscow Russian Federation 09 09 2024 09 09 2024 2024 3 27 33 03 09 2024 https://logospress.editorum.ru/en/nauka/article/88354/view

Применение лекарственного препарата Курс Успокоин таблетки в минимальной начальной суточной дозе 7 мг/кг первые три дня, с дальнейшим ее увеличением до 14 мг/кг показало положительный эффект при коррекции поведения кошек старше 10 лет с прогрессирующими признаками когнитивных нарушений. В ходе курсовой терапии у животных зарегистрировано статистически и клинически значимое снижение идиопатической вокализации, восстановление режима сна и бодрствования, устранение нечистоплотного поведения, дезориентации в пространстве, повышение активности, улучшение социального поведения. В ходе применения лекарственного препарата Курс Успокоин таблетки и после его отмены нежелательных реакций у животных не зарегистрировано.

The treatment by Kurs Uspokoin tablets in a minimum initial daily dose of 7 mg/kg for the first three days, with a further increase to 14 mg/kg, showed a positive effect in correcting the behavior of older cats with progressive simptoms of cognitive disfunction. During the treatment were registered a statistically and clinically significant decrease in idiopathic vocalization, restoration of sleep cycles and wakefulness, elimination of house-soiling behavior, disorientation, increased activity, and improvement of social behavior. During the treatment by Kurs Uspokoin tablets and after its discontinuation no adverse reactions were registered.

 сукцинат тразодона Курс Успокоин таблетки кошки возрастные когнитивные нарушения стареющие кошки серотониновая система нейромедиатор succinate trazodone Kurs Uspokoin tablets age-related cognitive impairment older cats serotonin system neurotransmitters

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