<!DOCTYPE article
PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20190208//EN"
       "JATS-journalpublishing1.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.4" xml:lang="en">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Russian veterinary journal</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Russian veterinary journal</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Российский ветеринарный журнал</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2500-4379</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">95532</article-id>
   <article-id pub-id-type="doi">10.32416/2500-4379-2025-1-36-40</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>СОВРЕМЕННЫЕ ФАРМАКО- И БИОПРЕПАРАТЫ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>MODERN PHARMACOLOGICAL DRUGS &amp; BIOPREPARATIONS</subject>
    </subj-group>
    <subj-group>
     <subject>СОВРЕМЕННЫЕ ФАРМАКО- И БИОПРЕПАРАТЫ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">Tolerability of the new drug Kurs Uspokoin tablets by cats in chronic experiment</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Переносимость нового лекарственного препарата Курс Успокоин таблетки кошками в условиях хронического опыта</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Белоглазов</surname>
       <given-names>Денис Валерьевич</given-names>
      </name>
      <name xml:lang="en">
       <surname>Beloglazov</surname>
       <given-names>Denis Valer'evich</given-names>
      </name>
     </name-alternatives>
     <bio xml:lang="ru">
      <p>кандидат биологических наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of sciences in biology;</p>
     </bio>
     <xref ref-type="aff" rid="aff-1"/>
     <xref ref-type="aff" rid="aff-2"/>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Мукасеев</surname>
       <given-names>Сергей Владимирович</given-names>
      </name>
      <name xml:lang="en">
       <surname>Mukaseev</surname>
       <given-names>Sergey Vladimirovich</given-names>
      </name>
     </name-alternatives>
     <bio xml:lang="ru">
      <p>кандидат ветеринарных наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of veterinary sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-4"/>
     <xref ref-type="aff" rid="aff-5"/>
     <xref ref-type="aff" rid="aff-6"/>
     <xref ref-type="aff" rid="aff-7"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Зейналов</surname>
       <given-names>Орхан Ахмедович</given-names>
      </name>
      <name xml:lang="en">
       <surname>Zeynalov</surname>
       <given-names>Orhan Ahmedovich</given-names>
      </name>
     </name-alternatives>
     <bio xml:lang="ru">
      <p>кандидат биологических наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of sciences in biology;</p>
     </bio>
     <xref ref-type="aff" rid="aff-8"/>
     <xref ref-type="aff" rid="aff-9"/>
     <xref ref-type="aff" rid="aff-10"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">ООО «НПК «СКиФФ»</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">LLC «NPC «SKiFF»</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">ООО «АГ «Аспект»</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">LLC AG Aspect</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">ООО «НВП «Астрафарм»</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">LLC «RDE «Astrapharm»</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-4">
    <aff>
     <institution xml:lang="ru">ООО «НПК «СКиФФ»</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">LLC «NPC «SKiFF»</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-5">
    <aff>
     <institution xml:lang="ru">ООО «АГ «Аспект»</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">LLC «AG «Aspect»</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-6">
    <aff>
     <institution xml:lang="ru">ООО «НВП «Астрафарм»</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">LLC «RDE «Astrapharm»</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-7">
    <aff>
     <institution xml:lang="ru">ООО «БиоФерон»</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">LLC «BioFeron»</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-8">
    <aff>
     <institution xml:lang="ru">ООО «НПК «СКиФФ»</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">LLC «NPC «SKiFF»</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-9">
    <aff>
     <institution xml:lang="ru">ООО «НВП «Астрафарм»</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">LLC «RDE «Astrapharm»</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-10">
    <aff>
     <institution xml:lang="ru">ООО «БиоФерон»</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">LLC «BioFeron»</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2025-03-10T17:49:41+03:00">
    <day>10</day>
    <month>03</month>
    <year>2025</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2025-03-10T17:49:41+03:00">
    <day>10</day>
    <month>03</month>
    <year>2025</year>
   </pub-date>
   <volume>2025</volume>
   <issue>1</issue>
   <fpage>36</fpage>
   <lpage>40</lpage>
   <history>
    <date date-type="received" iso-8601-date="2025-02-26T00:00:00+03:00">
     <day>26</day>
     <month>02</month>
     <year>2025</year>
    </date>
   </history>
   <self-uri xlink:href="https://logospress.editorum.ru/en/nauka/article/95532/view">https://logospress.editorum.ru/en/nauka/article/95532/view</self-uri>
   <abstract xml:lang="ru">
    <p>По результатам настоящего исследования установлено, что пероральное введение ЛП Курс Успокоин таблетки кошкам в течение 380 суток в дозах 18,0 мг/кг и 25,2 мг/кг не оказывает отрицательного влияния на их общее состояние и поведение, динамику массы тела, клинически значимо не изменяет температуру тела, частоту пульса и дыхания, морфологический состав и биохимические показатели крови.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Based on the results of this study, it was established that oral administration of the drug Course Uspokoin in tablets to cats for 380 days at doses of 18.0 mg/kg and 25.2 mg/kg does not have a negative effect on animals on their general condition and behavior, body weight dynamics , animal behavior. does not determine body temperature, measures pulse and population density, morphological composition and biochemical parameters of blood.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>сукцинат тразодона</kwd>
    <kwd>Курс Успокоин таблетки</kwd>
    <kwd>кошки</kwd>
    <kwd>хроническая токсичность</kwd>
    <kwd>переносимость</kwd>
    <kwd>безопасность</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>succinate trazodone</kwd>
    <kwd>Kurs Uspokoin tablets</kwd>
    <kwd>cats</kwd>
    <kwd>chronical toxicity</kwd>
    <kwd>tolerability</kwd>
    <kwd>safety</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
  <ref-list>
   <ref id="B1">
    <label>1.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Voith, V.L. Attachment of people to companion animals / V.L. Voith // Vet Clin North Am Small Anim Pract. ‒ 1985. ‒No. 15. ‒ pp. 289-295.</mixed-citation>
     <mixed-citation xml:lang="en">Voith, V.L. Attachment of people to companion animals / V.L. Voith // Vet Clin North Am Small Anim Pract. ‒ 1985. ‒No. 15. ‒ pp. 289-295.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B2">
    <label>2.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Patronek, G. Attitudes, procedures, and delivery of behavior services by veterinarians in small animal practice / G. Patronek, M. Dodman // J Am Vet Med Assoc. ‒ 1999. ‒ No. 215. ‒ pp. 1606-1611.</mixed-citation>
     <mixed-citation xml:lang="en">Patronek, G. Attitudes, procedures, and delivery of behavior services by veterinarians in small animal practice / G. Patronek, M. Dodman // J Am Vet Med Assoc. ‒ 1999. ‒ No. 215. ‒ pp. 1606-1611.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B3">
    <label>3.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Salman, M.D. Behavioral reasons for relinquishment of dogs and cats to 12 shelters / M.D. Salman, J. Hutchison, R. Ruch-Gallie, et al. // J Appl Anim Welf Sci. ‒ 2000. ‒ No. 3. ‒ pp. 93-106.</mixed-citation>
     <mixed-citation xml:lang="en">Salman, M.D. Behavioral reasons for relinquishment of dogs and cats to 12 shelters / M.D. Salman, J. Hutchison, R. Ruch-Gallie, et al. // J Appl Anim Welf Sci. ‒ 2000. ‒ No. 3. ‒ pp. 93-106.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B4">
    <label>4.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Scarlett, J.M. The role of veterinary practitioners in reducing dog and cat relinquishments and euthanasias / J.M. Scarlett, M.D. Salman, J.G. New, et al. // J Am Vet Med Assoc. ‒ 2002. ‒ No. 220. ‒ pp. 306-311.</mixed-citation>
     <mixed-citation xml:lang="en">Scarlett, J.M. The role of veterinary practitioners in reducing dog and cat relinquishments and euthanasias / J.M. Scarlett, M.D. Salman, J.G. New, et al. // J Am Vet Med Assoc. ‒ 2002. ‒ No. 220. ‒ pp. 306-311.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B5">
    <label>5.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Hammerle, M. AAHA canine and feline behavior management guidelines ‒ M. Hammerle, C. Horst, E. Levine, et al. // J Am Anim Hosp Assoc. ‒ 2015. ‒ No. 51. ‒ pp. 205-221.</mixed-citation>
     <mixed-citation xml:lang="en">Hammerle, M. AAHA canine and feline behavior management guidelines ‒ M. Hammerle, C. Horst, E. Levine, et al. // J Am Anim Hosp Assoc. ‒ 2015. ‒ No. 51. ‒ pp. 205-221.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B6">
    <label>6.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Seksel, K. Use of clomipramine in the treatment of anxiety-related and obsessive-compulsive disorders in cats / K. Seksel, M.J. Lindeman // Aust Vet J. ‒ 1998. ‒ No. 76. ‒ pp. 317-320.</mixed-citation>
     <mixed-citation xml:lang="en">Seksel, K. Use of clomipramine in the treatment of anxiety-related and obsessive-compulsive disorders in cats / K. Seksel, M.J. Lindeman // Aust Vet J. ‒ 1998. ‒ No. 76. ‒ pp. 317-320.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B7">
    <label>7.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Griffith, C.A. Effects of a synthetic facial pheromone on the behavior of cats / C.A. Griffith, E.S. Steigerwald, C.A.T. Buffington // J Am Vet Med Assoc. ‒ 2000. ‒ No. 217. ‒ pp. 1154-1156.</mixed-citation>
     <mixed-citation xml:lang="en">Griffith, C.A. Effects of a synthetic facial pheromone on the behavior of cats / C.A. Griffith, E.S. Steigerwald, C.A.T. Buffington // J Am Vet Med Assoc. ‒ 2000. ‒ No. 217. ‒ pp. 1154-1156.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B8">
    <label>8.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Pryor, P.A. Effects of a selective serotonin reuptake inhibitor on urine spraying behavior in cats / P.A. Pryor, B.L. Hart, K.D. Cliff, et al. // J Am Vet Med Assoc. ‒ 2001. ‒ No. 219. ‒ pp. 1557-1561.</mixed-citation>
     <mixed-citation xml:lang="en">Pryor, P.A. Effects of a selective serotonin reuptake inhibitor on urine spraying behavior in cats / P.A. Pryor, B.L. Hart, K.D. Cliff, et al. // J Am Vet Med Assoc. ‒ 2001. ‒ No. 219. ‒ pp. 1557-1561.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B9">
    <label>9.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Dramard, V. Clinical efficacy of L-theanine tablets to reduce anxiety-related emotional disorders in cats: a pilot open-label clinical trial / V. Dramard, L. Kern, J. Hofmans, et al. // J Vet Behav. ‒ 2007. ‒ No. 5. ‒ pp. 85-86.</mixed-citation>
     <mixed-citation xml:lang="en">Dramard, V. Clinical efficacy of L-theanine tablets to reduce anxiety-related emotional disorders in cats: a pilot open-label clinical trial / V. Dramard, L. Kern, J. Hofmans, et al. // J Vet Behav. ‒ 2007. ‒ No. 5. ‒ pp. 85-86.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B10">
    <label>10.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">van Haaften, K.A. Effects of a single preappointment dose of gabapentin on signs of stress in cats during transportation and veterinary examination / K.A. van Haaften, L.R.E. Forsythe, E.A. Stelow, et al. // J Am Vet Med Assoc. ‒ 2017. ‒ No. 251. ‒ pp. 1175-1181.</mixed-citation>
     <mixed-citation xml:lang="en">van Haaften, K.A. Effects of a single preappointment dose of gabapentin on signs of stress in cats during transportation and veterinary examination / K.A. van Haaften, L.R.E. Forsythe, E.A. Stelow, et al. // J Am Vet Med Assoc. ‒ 2017. ‒ No. 251. ‒ pp. 1175-1181.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B11">
    <label>11.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Sordo, L. Cognitive Dysfunction in Cats: Update on Neuropathological and Behavioural Changes Plus Clinical Management / L. Sordo, D.A. Gunn-Moore // Vet Rec. ‒ 2021 Jan. ‒ No. 188(1). ‒ e3. doi: 10.1002/vetr.3. Epub 2021 Jan 12. PMID: 34651755.</mixed-citation>
     <mixed-citation xml:lang="en">Sordo, L. Cognitive Dysfunction in Cats: Update on Neuropathological and Behavioural Changes Plus Clinical Management / L. Sordo, D.A. Gunn-Moore // Vet Rec. ‒ 2021 Jan. ‒ No. 188(1). ‒ e3. doi: 10.1002/vetr.3. Epub 2021 Jan 12. PMID: 34651755.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B12">
    <label>12.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Gunn-Moore, D. Cognitive dysfunction and the neurobiology of ageing in cats / D. Gunn-Moore, K. Moffat, L-A. Christie, E. Head // J Small Anim Pract. ‒ 2007. ‒ No. 48. ‒ pp. 546-53. https://doi.org/10.1111/j.1748- 5827.2007.00386.x.</mixed-citation>
     <mixed-citation xml:lang="en">Gunn-Moore, D. Cognitive dysfunction and the neurobiology of ageing in cats / D. Gunn-Moore, K. Moffat, L-A. Christie, E. Head // J Small Anim Pract. ‒ 2007. ‒ No. 48. ‒ pp. 546-53. https://doi.org/10.1111/j.1748- 5827.2007.00386.x.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B13">
    <label>13.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Landsberg, G.M. Cognitive dysfunction in cats: a syndrome we used to dismiss as ’old age’ / G.M. Landsberg, S. Denenberg, J.A. Araujo // J Feline Med Surg. ‒ 2010. ‒ No. 12. ‒ pp. 837-48.</mixed-citation>
     <mixed-citation xml:lang="en">Landsberg, G.M. Cognitive dysfunction in cats: a syndrome we used to dismiss as ’old age’ / G.M. Landsberg, S. Denenberg, J.A. Araujo // J Feline Med Surg. ‒ 2010. ‒ No. 12. ‒ pp. 837-48.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B14">
    <label>14.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Alcántara-López, M.G. Trazodone, an atypical antidepressant with anxiolytic and sedative properties / M.G. Alcántara-López, A.G. Gutiérrez-García, M. Hernández-Lozano, C.M. Contreras // Arch Neurocien. ‒ 2009. ‒ No. 14(4). ‒ pp. 249-257.</mixed-citation>
     <mixed-citation xml:lang="en">Alcántara-López, M.G. Trazodone, an atypical antidepressant with anxiolytic and sedative properties / M.G. Alcántara-López, A.G. Gutiérrez-García, M. Hernández-Lozano, C.M. Contreras // Arch Neurocien. ‒ 2009. ‒ No. 14(4). ‒ pp. 249-257.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B15">
    <label>15.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Cuomo, A. Trazodone: a multifunctional antidepressant. Evaluation of its properties and real-world use / A. Cuomo, A. Bianchetti, A. Cagnin // Journal of Gerontology and Geriatrics. ‒ 2021 june. ‒ Vol. 69. ‒ Iss. 2 16. Haria, M. Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders / M. Haria, A. Fitton, D. McTavish // Drugs Aging. ‒ 1994. ‒ No. 4(4). ‒ pp. 331.</mixed-citation>
     <mixed-citation xml:lang="en">Cuomo, A. Trazodone: a multifunctional antidepressant. Evaluation of its properties and real-world use / A. Cuomo, A. Bianchetti, A. Cagnin // Journal of Gerontology and Geriatrics. ‒ 2021 june. ‒ Vol. 69. ‒ Iss. 2 16. Haria, M. Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders / M. Haria, A. Fitton, D. McTavish // Drugs Aging. ‒ 1994. ‒ No. 4(4). ‒ pp. 331.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B16">
    <label>16.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Stahl, S.M. Mechanism of Action of Trazodone: a Multifunctional Drug / Stahl S.M. ‒ Published online by Cambridge University Press:  07 November 2014.</mixed-citation>
     <mixed-citation xml:lang="en">Stahl, S.M. Mechanism of Action of Trazodone: a Multifunctional Drug / Stahl S.M. ‒ Published online by Cambridge University Press:  07 November 2014.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B17">
    <label>17.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Fagiolini, A. Rediscovering Trazodone for the Treatment of Major Depressive Disorder / A. Fagiolini, A. Comandini // CNS Drugs. ‒ 2012. ‒ No. 26(12). ‒ pp. 1033-1049.</mixed-citation>
     <mixed-citation xml:lang="en">Fagiolini, A. Rediscovering Trazodone for the Treatment of Major Depressive Disorder / A. Fagiolini, A. Comandini // CNS Drugs. ‒ 2012. ‒ No. 26(12). ‒ pp. 1033-1049.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B18">
    <label>18.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Fagiolini, A. Rediscovering trazodone for the treatment of major depressive disorder / A. Fagiolini, A. Comandini, M. Catena Dell'Osso, S. Kasper // CNS Drugs. ‒ 2012 Dec. ‒ No. 26(12). ‒ pp. 1033-49.</mixed-citation>
     <mixed-citation xml:lang="en">Fagiolini, A. Rediscovering trazodone for the treatment of major depressive disorder / A. Fagiolini, A. Comandini, M. Catena Dell'Osso, S. Kasper // CNS Drugs. ‒ 2012 Dec. ‒ No. 26(12). ‒ pp. 1033-49.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B19">
    <label>19.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Khouzam, H.R. A review of trazodone use in psychiatric and medical conditions / H.R. Khouzam // Postgrad. Med. ‒ 2017. ‒ No. 129. ‒ pp. 140-148.</mixed-citation>
     <mixed-citation xml:lang="en">Khouzam, H.R. A review of trazodone use in psychiatric and medical conditions / H.R. Khouzam // Postgrad. Med. ‒ 2017. ‒ No. 129. ‒ pp. 140-148.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B20">
    <label>20.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Orlando, J.M. Use of oral trazodone for sedation in cats: A pilot study / J.M. Orlando, B.C. Case, A.E. Thomson, E. Griffith, B.L. Sherman // J. Feline Med. Surg. ‒ 2016. ‒ No. 18. ‒ pp. 476-482.</mixed-citation>
     <mixed-citation xml:lang="en">Orlando, J.M. Use of oral trazodone for sedation in cats: A pilot study / J.M. Orlando, B.C. Case, A.E. Thomson, E. Griffith, B.L. Sherman // J. Feline Med. Surg. ‒ 2016. ‒ No. 18. ‒ pp. 476-482.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B21">
    <label>21.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Stevens, B.J. Efficacy of a single dose of trazodone hydrochloride given to cats prior to veterinary visits to reduce signs of transport- and examination-related anxiety / B.J. Stevens, E.M. Frantz, J.M. Orlando, E. Griffi th, L.B. Harden et al. // J. Am. Vet. Med. Assoc. ‒ 2016. ‒ No. 249. ‒ pp. 202-207.</mixed-citation>
     <mixed-citation xml:lang="en">Stevens, B.J. Efficacy of a single dose of trazodone hydrochloride given to cats prior to veterinary visits to reduce signs of transport- and examination-related anxiety / B.J. Stevens, E.M. Frantz, J.M. Orlando, E. Griffi th, L.B. Harden et al. // J. Am. Vet. Med. Assoc. ‒ 2016. ‒ No. 249. ‒ pp. 202-207.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B22">
    <label>22.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Chea, В., Trazodone: A Review of its pharmacological properties and its off-label use in dogs and cats / В. Chea, M. Giorgi // American Journal of Animal and Veterinary Sciences. ‒ 2017. ‒ No. 12 (4). ‒ pp. 188-194.</mixed-citation>
     <mixed-citation xml:lang="en">Chea, V., Trazodone: A Review of its pharmacological properties and its off-label use in dogs and cats / V. Chea, M. Giorgi // American Journal of Animal and Veterinary Sciences. ‒ 2017. ‒ No. 12 (4). ‒ pp. 188-194.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B23">
    <label>23.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Orlando, J.M. Use of oral trazodone for sedation in cats: A pilot study / J.M. Orlando, B.C. Case, A.E. Thomson, E. Griffith, B.L. Sherman // J. Feline Med. Surg. ‒ 2016. ‒ No. 18. ‒ pp. 476-482.</mixed-citation>
     <mixed-citation xml:lang="en">Orlando, J.M. Use of oral trazodone for sedation in cats: A pilot study / J.M. Orlando, B.C. Case, A.E. Thomson, E. Griffith, B.L. Sherman // J. Feline Med. Surg. ‒ 2016. ‒ No. 18. ‒ pp. 476-482.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B24">
    <label>24.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Stevens, B.J. Efficacy of a single dose of trazodone hydrochloride given to cats prior to veterinary visits to reduce signs of transport- and examination-related anxiety / B.J. Stevens, E.M. Frantz, J.M. Orlando, E. Griffith, L.B. Harden et al. // J. Am. Vet. Med. Assoc. ‒ 2016. ‒ No. 249. ‒ pp. 202-207.</mixed-citation>
     <mixed-citation xml:lang="en">Stevens, B.J. Efficacy of a single dose of trazodone hydrochloride given to cats prior to veterinary visits to reduce signs of transport- and examination-related anxiety / B.J. Stevens, E.M. Frantz, J.M. Orlando, E. Griffith, L.B. Harden et al. // J. Am. Vet. Med. Assoc. ‒ 2016. ‒ No. 249. ‒ pp. 202-207.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B25">
    <label>25.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Белоглазов, Д.В. Тразодона сукцинат — новые возможности фармакологической коррекции ситуационных поведенческих отклонений у собак и кошек / Д.В. Белоглазов, С.В. Мукасеев, О.А. Зейналов // Российский ветеринарный журнал. ‒ 2021. ‒ № 4. ‒ С. 5-13.</mixed-citation>
     <mixed-citation xml:lang="en">Beloglazov, D.V. Trazodona sukcinat — novye vozmozhnosti farmakologicheskoy korrekcii situacionnyh povedencheskih otkloneniy u sobak i koshek / D.V. Beloglazov, S.V. Mukaseev, O.A. Zeynalov // Rossiyskiy veterinarnyy zhurnal. ‒ 2021. ‒ № 4. ‒ S. 5-13.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B26">
    <label>26.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Оробец, В.А. Токсикологическая характеристика нового препарата для ситуационной коррекции поведенческих отклонений у кошек и собак Экспресс Успокоин® таблетки / В.А. Оробец, Д.В. Белоглазов, С.В. Мукасеев, О.А. Зейналов // Российский ветеринарный журнал. ‒ 2023. ‒ № 1 ‒ С. 10-18.</mixed-citation>
     <mixed-citation xml:lang="en">Orobec, V.A. Toksikologicheskaya harakteristika novogo preparata dlya situacionnoy korrekcii povedencheskih otkloneniy u koshek i sobak Ekspress Uspokoin® tabletki / V.A. Orobec, D.V. Beloglazov, S.V. Mukaseev, O.A. Zeynalov // Rossiyskiy veterinarnyy zhurnal. ‒ 2023. ‒ № 1 ‒ S. 10-18.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B27">
    <label>27.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Белоглазов, Д.В. Оценка эффективности нового препарата Экспресс Успокоин® таблетки при ситуационной коррекции поведенческих проблем у собак / Д.В. Белоглазов, С.В. Мукасеев, О.А. Зейналов // Современная ветеринарная медицина. ‒ 2023. ‒ № 1. ‒ C. 18-22.</mixed-citation>
     <mixed-citation xml:lang="en">Beloglazov, D.V. Ocenka effektivnosti novogo preparata Ekspress Uspokoin® tabletki pri situacionnoy korrekcii povedencheskih problem u sobak / D.V. Beloglazov, S.V. Mukaseev, O.A. Zeynalov // Sovremennaya veterinarnaya medicina. ‒ 2023. ‒ № 1. ‒ C. 18-22.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B28">
    <label>28.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Белоглазов, Д.В. Оценка эффективности нового препарата Экспресс Успокоин® таблетки при ситуационной коррекции поведенческих проблем у кошек / Д.В. Белоглазов, С.В. Мукасеев, О.А. Зейналов // Российский ветеринарный журнал. ‒ 2023. ‒ № 2 ‒ С. 14-22.</mixed-citation>
     <mixed-citation xml:lang="en">Beloglazov, D.V. Ocenka effektivnosti novogo preparata Ekspress Uspokoin® tabletki pri situacionnoy korrekcii povedencheskih problem u koshek / D.V. Beloglazov, S.V. Mukaseev, O.A. Zeynalov // Rossiyskiy veterinarnyy zhurnal. ‒ 2023. ‒ № 2 ‒ S. 14-22.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B29">
    <label>29.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Елизарова Е.А., Белоглазов Д.В., Зейналов О.А., Мукасеев С.В., Оценка эффективности нового лекарственного препарата Курс Успокоин таблетки для коррекции возрастных когнитивных нарушений у кошек / Д.В. Белоглазов, О.А. Зейналов, С.В. Мукасеев // Российский ветеринарный журнал. ‒ 2024. ‒ № 3 ‒ С. 27-33.</mixed-citation>
     <mixed-citation xml:lang="en">Elizarova E.A., Beloglazov D.V., Zeynalov O.A., Mukaseev S.V., Ocenka effektivnosti novogo lekarstvennogo preparata Kurs Uspokoin tabletki dlya korrekcii vozrastnyh kognitivnyh narusheniy u koshek / D.V. Beloglazov, O.A. Zeynalov, S.V. Mukaseev // Rossiyskiy veterinarnyy zhurnal. ‒ 2024. ‒ № 3 ‒ S. 27-33.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B30">
    <label>30.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Settimo, L. Evaluating the dose-dependent mechanism of action of trazodone by estimation of occupancies for different brain neurotransmitter targets / L. Settimo, D. Taylor // Journal of Psychopharmacology. ‒ 2018. ‒ No. 32(1). ‒ pp. 96-104.</mixed-citation>
     <mixed-citation xml:lang="en">Settimo, L. Evaluating the dose-dependent mechanism of action of trazodone by estimation of occupancies for different brain neurotransmitter targets / L. Settimo, D. Taylor // Journal of Psychopharmacology. ‒ 2018. ‒ No. 32(1). ‒ pp. 96-104.</mixed-citation>
    </citation-alternatives>
   </ref>
  </ref-list>
 </back>
</article>
