Russian veterinary journal Russian veterinary journal Российский ветеринарный журнал 2500-4379 106837 УРОЛОГИЯ UROLOGY УРОЛОГИЯ Effects of two calculolytic diets on parameters of feline mineral metabolism Влияние двух рационов, предназначенных для растворения камней, на параметры минерального обмена у кошек Пинеда С. Pineda S. Агилера-Тейеро Е. Agilera-Teyero E. Райа А.-И. Raya A.-I. Монтесде-Ока А. Montesde-Oka A. Родригес М. Rodriges M. Лопес И. Lopes I. Университет Кордовы Кордова Испания Universidad de Cordoba Cordoba Spain Университет Кордовы Кордова Испания Universidad de Cordoba Cordoba Spain Университет Кордовы Кордова Испания Universidad de Cordoba Cordoba Spain Университет Кордовы Кордова Испания Universidad de Cordoba Cordoba Spain Институт биомедицинских исследований им. Маймонида Кордова Испания Instituto Maimonides para la Investigacion Biomedica (IMIBIC) Cordoba Spain Университет Кордовы Кордова Испания Universidad de Cordoba Cordoba Spain 19 11 2025 19 11 2025 2025 4 60 66 19 11 2025 https://logospress.editorum.ru/en/nauka/article/106837/view

Цели: оценить влияние двух рационов, предназначенных для растворения камней, на избранные параметры минерального обмена у кошек. Материалы и методы: два готовых сухих корма, предназначенных для растворения струвитных уролитов, исследовались на 14 кошках. Исследование запланировано как перекрестное с двумя последовательностями и четырьмя периодами: исходным периодом, двумя 60-дневными «вводными периодами», во время которых животных кормили рационом для растворения уролитов (корм 1 и корм 2), и одним 30-дневным «периодом вымывания». Данные представлены как медиана (диапазон). Клиническая значимость: оба корма привели к повышению концентрации магния в моче по разным механизмам: подкисление мочи (корм 1) и повышение натриевой нагрузки (корм 2).

Objectives: To evaluate the influence of two feline calculolytic diets on selected parameters of mineral metabolism. Materials and methods: Two dry commercial diets designed for struvite urolith dissolution were evaluated in 14 cats. The study was designed as a two-sequence, four-period crossover protocol with a baseline period, two 60-day «run-in» periods in which calculolytic diets (Diet 1 and Diet 2) were fed and one 30-day «wash-out» period. Data are expressed as median (range). Results: Feeding the calculolytic diets for two months did not alter plasma concentrations of calcium, phosphorus, magnesium and parathyroid hormone. A significant (P<0·05 in each case) decline in calcitriol was observed after administering both diets from 236·4 (122·4–429·6) to 170·4 (108·0–394·3) pmol/L (Diet 1) and from 278·4 (153·6–492·0) to 177·1 (87·6–392·4) pmol/L (Diet 2). Cats fed Diet 1 showed a significant increase in urine calcium concentration (from 0·3 (0·2–0·5) to 0·4 (0·3–0·7) mmol/L). Magnesium concentration in urine was significantly increased with both diets, from 1·4 (0·1–1·7) to 1·5 (1·3–2·4) mmol/L (Diet 1) and from 1·1 (0·4–1·9) to 2·0 (0·1–3·1) mmol/L (Diet 2). Clinical significance: Both diets resulted in an increased urinary concentration of magnesium, through different mechanisms: urine acidification (Diet 1) and increased sodium load (Diet 2).

 кошки рацион минеральный обмен растворение камней cats diet mineral metabolism stone dissolution

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