from 01.01.2019 to 01.01.2025
Research Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical and Biological Agency (RIHOPHE) (Laboratory of molecular toxicology and experimental therapy, Leading Researcher)
Sankt-Peterburg, St. Petersburg, Russian Federation
CSCSTI 68.41
«Wet belly» in young sables kept in cages is an economically significant problem in modern fur farming in Russia. The incidence of disease in young sables can reach 6 %. The technological cycle of cage breeding of sables does not provide for vaccinations and other diagnostic procedures due to the animals' active reaction to external stimuli and the high risk of stress for the animals. In this regard, when diagnosing «wet belly» in young sable, the veterinary intervention protocol provides only for local aerosol treatment with antimicrobial drugs. There are few studies on the etiology and pathogenesis of «wet belly» in young sable. The causes and pathophysiological mechanisms of the development of «wet belly», in particular, the mechanisms of urinary dysfunction and urinary incontinence, remain unknown. In our work, we analyzed urine and pathological autopsy data from 76 young sables diagnosed with «wet belly». As a result, the animals were found to have concomitant pathology of the digestive and respiratory systems, as well as histological signs of cystitis and probable Escherichia coli infection of the urinary tract. However, in 26 % of males and 33 % of females, no pathology of the internal organs or urinary system was detected. Such findings require further investigation into the causes and mechanisms of the disease.
sable, urinalysis, pathology, «wet belly», urinary incontinence, autopsy, histology
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