LLC AG Aspect (Scientific consultant)
LLC «RDE «Astrapharm» (Scientific consultant)
Russian Federation
«Center of the veterinary aid» (Main veterinarian)
FSBEIo HE «Nizhny Novgorod State Agrotechnological University named after L.Ya. Florentiev» (NNSAU) (Department of anatomy, surgery and internal diseases, Associate Professor)
employee
Russian Federation
LLC «AG «Aspect» (Veterinarian)
LLC «RDE «Astrapharm» (Leading veterinarian)
LLC «BioFeron» (Leading veterinarian)
employee
Russian Federation
employee
Russian Federation
LLC «RDE «Astrapharm» (Chief science specialist)
LLC «BioFeron» (Chief science specialist)
employee
Russian Federation
CSCSTI 68.41
The results of the study demonstrated a high safety profile of the combined use of gabapentin at a dose of 4.5-6 mg/kg and succinate trazodone at a dose of 1.5-2 mg/kg twice daily for 14 days in cats with chronic kidney disease. During a 14-day course of treatment with Trazapentine® in cats with chronic kidney disease (CKD) stages 1-3 (creatinine 136–556 µmol/L), no adverse reactions associated with the drug were recorded. The differential effectiveness of Trazapentine® was established depending on the stage of CKD. Administration of the drug to cats with stages 1 and 2 renal failure resulted in a clinically and statistically significant improvement in quality of life.
cats, chronic kidney disease, trazodone succinate, gabapentin, Trazapentine®, efficacy, safety, quality of life
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