Russian Federation
Russian Federation
CSCSTI 68.41
The purpose of the study: clinical evaluation of the effectiveness of Ophthalmica eye drops in the prevention of infectious complications during various operations on the eyeball in dogs and cats. Materials and methods: Two groups of pets were formed, which underwent various ophthalmic operations: the experimental (n=17) and the control (n=18). The pets of the experimental group were treated with Ophthalmica eye drops for preventive purposes 3 times a day one day before surgery and in the postoperative period for up to 14 days (depending on the complexity of surgery and the severity of the initial eye). The pets of the control group were instilled with only a 5% aqueous solution of povidone-iodine. Results: The pets of the experimental group did not have any post-operative septic complications. There were no inflammatory phenomena in the form of purulent excretions from the conjunctival cavity. No eye was observed in any animal with edema, cornea clouding, or excesses in the front chamber. While the pets in the control group had oily complications, corneal edema, transplant disease. Conclusions: The use of Ophthalmica eye drops is a highly effective method of preventing infectious complications during various operations on the eyeball in dogs and cats.
Ophthalmica eye drops, gatifloxacin, efficacy, cats, dogs
1. Pavlova, T.N. Keratoplastika v veterinarnoy oftal'mologii/ T.N. Pavlova: diss. … kand. med. Nauk. – M., 2013. – 155s.
2. Shilkin, A.G. Korneal'nyy sekvestr, etiopatogenez, diagnostika i lechenie / A.G. Shilkin, E.P Kopenkin // Veterinar. – 1999. ‒ № 7-8yu – S. 34-36.
3. Shilkin, A.G. Sravnitel'naya effektivnost' razlichnyh glaznyh form ftorhinolonov v veterinarnoy oftal'mologii / A.G. Shilkin, E.P Kopenkin, V.V. Oleynik, S.V. Smirnova // Materialy XIV Moskovskogo mezhdunarodnogo veterinarnogo kongressa po boleznyam melkih domashnih zhivotnyh. ‒ 22-24 aprelya, 2006. ‒ S. 158-161.
4. Engashev, S.V. Farmakokinetika lekarstvennogo preparata OFTAL'MIKA® kapli glaznye / S.V. Engashev, E.S. Engasheva, A.A. Komarov [i dr.] // Veterinarnyy farmakologicheskiy vestnik. – 2025. – № 2(31). – S. 46-56.
5. Liu, M. Comparative Study of Ocular Pharmacokinetics of Topical 0.3% Gatifloxacin Eye Gel and Solution in Rabbits / M. Liu [at al.] // Antibiotics. ‒ 2022. ‒ V. 11. ‒ pp. 502.
6. Liu, X. Determination of drug concentration in aqueous humor of cataract patients administered gatifloxacin ophthalmic gel. / X. Liu [at al.] // Chin Med J (Engl). – 2010. – No. 123. – pp. 2105-2110.
7. Maggs, D.J. Slatter’s fundamentals of veterinary ophthalmology / D.J. Maggs, P.E. Miller, R. Ofri. – Saunders Elsevier: St. Louis. Mo. 2013. ‒ 506 p.
8. Vipul Bhandary Jagdeesh K. Studying the Efficacy of Gatifloxacin 0.5% Eye Drops Preoperatively in Decreasing the Colony Forming Units (CFU) in Conjunctival Cultures / Vipul B. Jagdeesh K. // Clinical Microbiology. – 2015 Jan. – pp. 102-112. DOIhttps://doi.org/10.4172/2327-5073.1000209



