employee
Russian Federation
graduate student
Russian Federation
GRNTI 68.41 Ветеринария
In this article we present the results of studies aimed at establishing the level of post-vaccination antibodies to parvovirus enteritis. The work was performed on dogs 1.5…2 months old. The animals were divided into two groups. In the first group, dogs were vaccinated and treated against endoparasites according to all instructions. Dogs of the second group were also vaccinated, but were not exposed to anthelmintic treatments. Further, the state of the experimental animals was monitored with the methods of clinical examination, coproscopic, hematological, biochemical and serological researches. Dogs not treated against endoparasites showed symptoms of parvovirus enteritis by the 6th day of the experiment. Coproscopic research indicated an invasion of Toxocara canis by nematodes. Hematological research showed a decrease in the level of hemoglobin, hematocrit and platelets. The results of biochemical research showed a decrease in the level of albumin and total protein. During a serological research (ELISA), the development of extremely low antibody titers was noted. The dogs of the first group did not show any signs of deterioration in health. Indicators of hematology and biochemistry were within the physiological norm. The ELISA results indicated the development of antibodies to parvovirus enteritis. This research confirms the need for anthelmintic treatments before vaccinations.
post-vaccination immunity, vaccination, parvovirus enteritis, canine distemper, dogs
1. Astrahancev, V.I. Bolezni sobak / V.I. Astrahancev, E.P. Danilov, V.A. Pankov [i dr.] / Pod red. S. Ya. Lyubashenko. - M.: Kolos, 1988. - 327 s.
2. Balabanova, V. I. Patomorfologiya parvovirusnogo enterita sobak: avtoref. dis. … kand. veterinarnyh nauk : 16.00.02 / FGOU VPO «Sankt-Peterburgskaya gosudarstvennaya akademiya veterinarnoy mediciny». - Sankt-Peterburg, 2005. - 24 s.
3. Virusnye bolezni zhivotnyh / V.N. Syurin, A.Ya. Samuylenko, B.V. Solov'ev [i dr.]. - M.: VNITIBP, 1998. - S. 554-570.
4. Gerasimchik, V.A. Effektivnost' «Kvantuma» pri nekotoryh gel'mintozah sobak / V.A. Gerasimchik, O.Yu. Zybina, E.S. Eremeev //Agrarnaya nauka. - 2019. - № 4. - S. 26-28.
5. Daugalieva, E.H. Immunnyy status i puti ego korrekcii pri gel'mintozah sel'skohozyaystvennyh zhivotnyh / E.H. Daugalieva, V.V. Filippov. - M : Agropromizdat, 1991. - 188 s.
6. Durymanov, A.G. Lokalizaciya i likvidaciya epizootiy parvovirusnogo enterita sobak: tez. dokl. 1-y region. konf. po boleznyam melkih domashnih zhivotnyh / A.G. Durymanov, A.M. Shestopalov. - Krasnoyarsk, 1996. - S. 3-5.
7. Infekcionnaya patologiya zhivotnyh / Pod red. A.Ya. Samuylenko. - M.: Akademkniga, 2006. - S. 600-606.
8. Maksimov, N.A. Lechenie sobak pri parvovirusnom enterite / N.A. Maksimov // Veterinariya. - 1989. - № 5. - S. 72-73.
9. Marchenko, E.V. Parvovirusnyy enterit sobak, oslozhnennyy associaciyami uslovno patogennyh bakteriy (etiologiya, epizootologiya, patogenez i lechenie): avtoref. dis. … kand. veterinarnyh nauk: 06.02.02 / Luganskiy nacional'nyy agrarnyy universitet. - N. Novgorod, 2017. - 24 s.
10. Patent Ukrainy № 26241 «Sposob ekspress-diagnostiki eymeriidozov i nematodozov plotoyadnyh zhivotnyh» / V.A. Gerasimchik, V.F. Galat // Zayavl. 23.04.2007 g., № 20872/3, opubl. 10.09.2007 g., byulleten' № 14.
11. Patologoanatomicheskaya diagnostika virusnyh bolezney zhivotnyh: sprav. izd. / N.I. Arhipov, S.F. Chevelev, G.I. Bragin [i dr.]. - M.: Kolos, 1984. - S. 163-166.
12. Poletaeva, O.G. Fenomen rozetkoobrazovaniya V-limfocitami selezenki myshey, invazirovannyh lichinkami Ascaris suum / O.G. Poletaeva // Med. parazitol. i parazitarn. bolezni. - 1978. - № 4. - S. 34-38.
13. Syurin, V.N. Diagnostika virusnyh bolezney zhivotnyh: sprav. / V.N. Syurin, R.V. Belousova, N.V. Fomina. - M.: Agropromizdat, 1991. - S. 494-500.
14. Chermoshenceva, G.V. Kliniko-morfologicheskoe obosnovanie effektivnosti primeneniya gamavit forte pri lechenii bol'nyh babeziozom i parvovirusnym enteritom sobak : avtoref. … dis. kand. veterinarnyh nauk: 06.02.01 / FGBOU VPO «Saratovskiy gosudarstvennyy agrarnyy universitet im. N. I. Vavilova». - Saratov, 2012. - 23 s.
15. Yakubovskiy, M.V. Osobennosti immuniteta pri associativnyh parazitozah zheludochno-kishechnogo trakta telyat / M.V. Yakubovskiy, T.Ya. Myascova, V.P. Olenich // Teoriya i praktika bor'by s parazitarnymi boleznyami: materialy nauch. konf., Moskva, 16 -18 maya 2012 g. - Moskva, 2012. - S. 468-472.
16. Schultz, R.D. Chuma plotoyadnyh i parvovirusnaya infekciya sobak v usloviyah priyuta / R.D. Schultz // Journal of Small Animal Practice. - 2011. - Vol. 2, is. 4. - pp. 44.
