Russian Federation
GRNTI 68.41 Ветеринария
Unsaturated fatty acids cannot be synthesized in the body and, therefore, must be obtained with food. In dogs, they include linoleic and α-linolenic acid; in cats, linoleic, α-linolenic and arachidonic acid. Fatty acids are usually used orally to reduce skin inflammation, reduce itching caused by atopic dermatitis, and improve the barrier function of the skin. The characteristics of some immuno-mediated diseases (sebadennitis, lupoid onychodystrophy, discoid lupus erythematosus) and the means of therapy for them, including unsaturated fatty acids, are given.
immuno-mediated diseases, unsaturated fatty acids, dogs, cats
1. Martinez N., McDonald B., Martínez-Taboada F., Exploring the use of essential fatty acids in veterinary dermatology, Veterinary Record, 2020 Sep, Vol. 5, No. 187(5), pp. 190. doi:https://doi.org/10.1136/vr.105360.
2. Rosser E.J., Bonagura J.D., Therapy for sebaceous adenitis, In: Kirk's current veterinary therapy XIV, Philadelphia: Saunders, 2009, 451-453.
3. Auxilia S.T., Hill P.B., Thoday K.L., Canine symmetrical Lupoid onychodystrophy: a retrospective study with particular reference to management, J Small Anim Pract., 2001. No. 42, pp. 82-87.
4. Linder K.E., Banovic F., Olivry T., Cutaneous lupus erythematosus in dogs: a comprehensive review, BMC Veterinary Research, 2018, No. 14, pp. 132. https://doi.org/10.1186/s12917-018-1446-8
5. van Amersfort K., van der Lee A., Hagen-Plantinga E., Evidence-base for the beneficial effect of nutraceuticals in canine dermatological immune-mediated inflammatory diseases - A literature review. Vet Derm, 2023, available at https://doi.org/10.1111/vde.13152
6. Steimer T., Bauer A., Kienzle E., Mueller R.S., Canine symmetrical lupoid onychomadesis in bearded collies. Vet Derm 2019. https://doi.org/10.1111/vde.12779
7. Glos K., von Bomhard W., Bettenay S., Mueller R.S., Sebaceous adenitis and mural folliculitis in a cat responsive to topical fatty acid supplementation, Veterinary Dermatology, 2016 Feb, No. 27(1), 57-e18. doi:https://doi.org/10.1111/vde.12282.
