employee
Russian Federation
employee
Russian Federation
employee
Russian Federation
employee
Russian Federation
LLC «AG «Aspect» (Veterinarian)
LLC «RDE «Astrapharm» (Leading veterinarian)
LLC «BioFeron» (Leading veterinarian)
employee
Russian Federation
LLC «RDE «Astrapharm» (Chief science specialist)
LLC «BioFeron» (Chief science specialist)
employee
Russian Federation
68.41
This article presents the results of evaluating the efficacy of the veterinary spot-on Forsecto® for the treatment and prevention of infestation of dogs with ixodid ticks, fleas, lice, chewing lice and protection against attacks by blood-sucking mosquitoes. The efficacy of Forsecto® against spontaneous infestation with ixodid ticks was 100 % for 42 days after a single treatment. The death of 100% of ectoparasites was recorded 24 hours after treatment. The efficacy of Forsecto® against spontaneous infestation with fleas, lice and chewing lice was 100 % for 56 days after a single treatment. The death of 100 % of fleas was recorded after 24 hours, lice and chewing lice after 7 days after treatment. Forsecto® has a pronounced knockdown effect, which occurs 2.26…2.75 minutes after the contact of ixodid ticks with the fur of an animal treated with the drug and is recorded for at least 21 days. Forsecto® has a repellent effect against blood-sucking mosquitoes Aedes spp. and Culex spp., which lasts for at least 10 days. When monitoring the clinical condition of animals during the period of drug use, no adverse reactions were recorded.
Forsecto®, etofenprox, tebufenpyrad, dogs, ixodid ticks, fleas, lice, lice, acaricidal efficacy, insecticidal efficacy, therapeutic efficacy, prophylactic efficacy, safety, knockdown effect, repellent effect
1. Glazunova, L.A. Sravnitel'naya effektivnost' preparatov pri bloshinoy invazii sobak i koshek / L.A. Glazunova, Yu.A. Tkacheva // Veterinarnyy vrach. ‒ 2017. ‒№ 5. ‒ S. 44-48.
2. Gucevich, A.V. Komary (Semeystvo Culicidae) / A.V. Gucevich, A.S. Monchadskiy, A.A. Shtakel'berg. ‒ Fauna SSSR. Nasekomye dvukrylye. ‒ T. 3. ‒ Vyp. 4. ‒L.: Nauka, 1970. ‒ 384 s.
3. Devyat'yarova, S.B. Sovremennaya situaciya po ektoparazitozam sobak v Moskovskom megapolise / S.B. Devyat'yarova // Rossiyskiy parazitologicheskiy zhurnal. ‒ 2023. ‒ Vyp. 17. ‒ № 2. ‒ S. 224-228.
4. Zakusimova, K.S. Rasprostranenie i metody bor'by s ektoparazitami plotoyadnyh zhivotnyh / K.S. Zakusimova, A.V. Semenko // Nauchnyy vestnik. Seriya: Veterinarnaya medicina, kachestvo i sohrannost' produkcii zhivotnovodstva. ‒ 2018. ‒ № 293. ‒ S. 167-174.
5. Zubareva, I.M. Epizootologicheskaya harakteristika ektoparazitozov plotoyadnyh zhivotnyh megapolisa (na primere Novosibirska) / I.M. Zubareva, N.V. Yudina, E.A. Efremova // Teoriya i praktika bor'by s parazitarnymi boleznyami. ‒ 2023. ‒ № 24. ‒ S. 184-188.
6. Kruglov, D.S. Vstrechaemost' ktenocefalidoza u sobak i koshek v usloviyah goroda Tyumeni / D.S. Kruglov, O.A. Stolbova // Vestnik Gosudarstvennogo agrarnogo universiteta Severnogo Zaural'ya. – 2017. – № 2 (37). – S. 67-70.
7. Kruglov, D.S. Vstrechaemost' iksodovyh kleschey u sobak na fone primeneniya akaricidnyh sredstv / D.S. Kruglov, O.A. Stolbova // APK: innovacionnye tehnologii. ‒ 2019. ‒ № 4. ‒ S. 16-20.
8. Lyutikova, I.A. Ktenocefalidoz sobak i koshek megapolisa Moskvy: rasprostranenie, patogenez, terapiya: diss. ... kand. vet. nauk: 03.00.19 / Lyutikova Irina Anatol'evna; [Mesto zaschity: Vseros. nauch.-issled. in-t gel'mintologii im. K. I. Skryabina]. ‒ Moskva, 2008. ‒ 160 s.
9. Metody opredeleniya effektivnosti insekticidov, akaricidov, regulyatorov razvitiya i repellentov, ispol'zuemyh v medicinskoy dezinsekcii. Metodicheskie ukazaniya. MU 3.5.2.1759-03 / utv. Glavnym gosudarstvennym sanitarnym vrachom RF 28.09.2003.
10. Mukaseev, S.V. Issledovanie perenosimosti lekarstvennogo preparata Forsecto® pri nakozhnom primenenii sobakam / S.V. Mukaseev, S.A. Parhomenko, O.A. Zeynalov // Rossiyskiy veterinarnyy zhurnal. ‒ 2025. ‒ № 1. – S. 22-26. – DOIhttps://doi.org/10.32416/2500-4379-2025-1-20-26.
11. Orobec, V.A. Toksikologicheskaya harakteristika novogo insektoakaricidnogo lekarstvennogo preparata dlya sobak i koshek Forsecto® / V.A. Orobec, O.I. Sevost'yanova, E.S. Kastarnova, S.V. Mukaseev, O.A. Zeynalov // Rossiyskiy veterinarnyy zhurnal. ‒ 2024. ‒ № 3. ‒ S. 32-43. DOI:https://doi.org/10.32416/2500-4379-2024-4-32-43.
12. Plavil'schikov, N.N. Opredelitel' nasekomyh / N.N. Plavil'schikov. ‒ M., 1957. ‒ S. 304-305.
13. Serdyukova, G.V. Iksodovye kleschi fauny SSSR/ G.V. Serdyukova. ‒ M.-L.: Akademiya nauk SSSR, 1956. ‒ 122 s.
14. Schepot'eva, O.D. Ektoparazity melkih domashnih zhivotnyh / O.D. Schepot'eva, L.Yu. Porfir'eva, O.A. Panova, I.G. Glamazdin // Teoriya i praktika bor'by s parazitarnymi boleznyami. ‒ 2018. ‒ №19. ‒ S. 533-535.
15. Background document to the Opinion proposing harmonised classification and labelling at EU level of Tebufenpyrad. Annex 1 [Elektronnyy resurs]. – URL: https://echa.europa.eu/documents/10162/544e7470-8ae2-dc93-554a-7c74daea5dc3 (data obrascheniya 28.02.2024).
16. Bowman, D.D. Arthropods. Georgi’s Parasitology for Veterinarians / D.D. Bowman, W.B. Saunders Philadelphia, PA, USA, 2008. ‒ 422 p.
17. Bremer, W.G. Transstadial and intrastadial experimental transmission of Ehrlichia canis by male Rhipicephalus sanguineus / W.G. Bremer, J.J. Schaefer, E.R. Wagner, S.A. Ewing, Y. Rikihisa, G.R. Needham et al. // Vet Parasitol. ‒ 2005. ‒ No. 131. ‒ pp. 95-105. doi:https://doi.org/10.1016/j.vetpar.2005.04.030.
18. Davoust, B., Assay of fipronil to prevent canine monocytic ehrlichiosis in endemic areas / B. Davoust, J.L. Marie, S. Mercier, M. Boni, A. Vandeweghge, D. Parzy, F. Beugnet // Vet. Parasitol. ‒ 2003. ‒ No. 112. ‒ pp. 91-100.
19. Dryden, M.W. Host association: on-host longevity and egg production of Ctenocephalides felis / M.W. Dryden // Vet. Parasitol. ‒ 1989. ‒ No. 34. ‒ pp. 117-122.
20. Dryden, M.W. Biology and control of ticks infesting dogs and cats in North America / M.W. Dryden, P.A. Payne // Vet. Therap. ‒ 2004. ‒ No. 5. ‒ pp. 139-154.
21. EFSA Scientific Report 192, 1-99 Conclusion on the peer review of tebufenpyrad, 2008 [Elektronnyy resurs]. – URL: https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2009.192r (data obrascheniya 28.02.2024).
22. Fact Sheet for Pet Owners and Veterinarians about Potential Adverse Events Associated with Isoxazoline Flea and Tick Products [Elektronnyy resurs]. – URL: https://www.fda.gov/animal-veterinary/animal-health-literacy/fact-sheet-pet-owners-and-veterinarians-about-potential-adverse-events-associated-isoxazoline-flea (data obrascheniya 28.02.2024).
23. Fourie, J.J. Transmission of Ehrlicia canis by Rhipicephalus sangiuneus ticks feeding on dogs and on artificial membranes / J.J. Fourie, D. Stanneck, H.G. Luus, F. Beugnet, M. Wijnveld, F. Jongejan // Vet. Parasitol. ‒ 2013. ‒ No. 197. ‒ pp. 595-603.
24. IRAC Mode of Action Classification. Insecticide Resistance Action Committee [Elektronnyy resurs]. – URL: https://irac-online.org/mode-of-action/classification-online/ (data obrascheniya 28.02.2024).
25. Khambay, B.P.S. Pyrethroids / B.P.S. Khambay, P.J. Jewess. In Comprehensive Molecular Insect Science, 2005. ‒ pp. 1-29. doihttps://doi.org/10.1016/b0-44-451924-6/00075-2.
26. Krämer, F. Flea Biology and Control / F. Krämer, N. Menke. ‒ Berlin: Springer, 2001, 192 p.
27. Mencke, N. Future challenges for parasitology: vector control and ‘One health’ in Europe. The veterinary medicinal view on CVBDs such as tick borreliosis, rickettsiosis and canine leishmaniosis / N. Menke // Vet. Parasitol. ‒ 2013. ‒ No. 195. ‒ pp. 256-271.
28. Otranto, D. Managing canine vector-borne diseases of zoonotic concern: part one / D. Otranto, F. Dantas-Torres, E.B. Breitschwerdt // Trends Parasitol. ‒ 2009 Apr. ‒ No. 25(4). ‒ pp. 157-63.
29. Otranto, D. Managing canine vector-borne diseases of zoonotic concern: part two / D. Otranto, F. Dantas-Torres, E.B. Breitschwerdt // Trends Parasitol. ‒ 2009 May. ‒ No. 25(5). ‒ pp. 228-35.
30. Rust, M.K., The biology, ecology, and management of the cat flea / M.K. Rust, M.W. Dryden // Annu. Rev. Entomol. ‒ 1997. ‒ No. 42. ‒ pp. 451-473.
31. Schein, E. Electron microscopical studies on the development of Babesia canis (Sporozoa) in the salivary glands of the vector tick Dermacentor reticulatus / E. Schein, H. Mehlhorn, W.P. Voigt // Acta Trop. ‒ 1979. ‒ No. 36. ‒ pp. 229-241.
32. Varloud, M. Early Babesia canis transmission in dogs within 24 h and 8 h of infestation with infected pre-activated male Dermacentor reticulatus ticks / M. Varloud, J. Liebenberg, J. Fourie // Parasit Vectors. ‒ 2018 Jan. ‒ Vol. 17. ‒ No. 11(1). ‒ pp. 41. doi:https://doi.org/10.1186/s13071-018-2637-7.
