сотрудник с 01.01.2023 по настоящее время
ГБУЗ «Областная клиническая специализированная психоневрологическая больница №1» (Клиническое отделение первого психотического эпизода, Заведующий клиническим отделением)
сотрудник
Россия
ВАК 3.1.24 Неврология
ГРНТИ 76.29 Клиническая медицина
Целью настоящего исследования является проведение нарративного анализа научно-исследовательской литературы, направленного на изучение длительности нелеченого психоза в качестве прогностического фактора эффективности терапии и долговременного прогноза расстройств шизофренического спектра. Материалы и методы: обзор выполнен на основе систематического поиска в научно-исследовательских базах данных за 2019–2025 годы с анализом более 189 оригинальных работ, метаанализов и систематических обзоров. Результаты и обсуждение: установлена устойчивая связь длительного периода нелеченого психоза с выраженностью негативной симптоматики, когнитивного дефицита, снижением социального функционирования и высоким суицидальным риском. Внедрение программ раннего вмешательства, сокращающих данный интервал, ассоциирован с хорошим ответом на терапию и благоприятным течением заболевания. Заключение. Длительность нелеченого психоза является весомым фактором, определяющим прогноз заболевания, что обосновывает необходимость реорганизации психиатрической помощи в сторону превентивных моделей. Реализация комплексных мер, включающих раннее выявление, просвещение и оптимизацию маршрутизации пациентов, способна смягчить негативные последствия и улучшить исходы.
длительность нелеченого психоза, шизофрения, раннее вмешательство, расстройства шизофренического спектра, первый психотический эпизод
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